The Agilent/ Aurora SFC Fusion A5 is responsible for all tasks connected to pre- and post-conditioning of the mobile phase. In contrast, flow rate, mobile phase composition, detection, column temperature and data analysis are controlled by the modules of the Agilent 1260 Infinity SFC system in combination with the ChemStation software. This includes metering the carbon dioxide flow and mixing the modifier into the mobile phase by the HPLC-SFC binary pump.
In detail, the SFC Fusion A5 uses vapor-phase carbon dioxide, redestills it to the liquid state and boosts its pressure to just under the column head pressure. Since the CO2 gas is a very poor solvent, most contaminants in the carbon dioxide are left in the source, which allows for the use of inexpensive, beverage-grade CO2, unlike in any other commercially available instrument. SFC Fusion A5 further recollects the effluent from the UV (or other) detector and controls the backpressure up to 400 bar over the complete system. In addition, SFC Fusion A5 delivers the wash solvent to flush the fixed (sample) loop of the SFC Autosampler.
