The CD-2095 has been developed as an innovative CD (Circular Dichroism) detector, using the same technology applied in conventional CD spectropolarimeters, but optimized to meet HPLC requirements. The CD-2095 detector can simultaneously determine both CD and UV absorption of the sample in the same cell for direct determination of optical purity. CD is based on the differential absorption of right and left circularly polarized light due to the existence of a chiral chromaphore and is a much more specific technique than OR (Optical Rotation) or Polarimetry. In the past, large and expensive CD spectropolarimeters have often been modified for use as a CD detector in an HPLC systems. The CD-2095 can easily be interfaced with the JASCO HPLC system using the JASCO chromatography data systems.